Which opioid is primarily metabolized by plasma esterases?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Study for the Oral and Maxillofacial Surgery In-Service Training (OMSITE) Test. Prepare with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

Multiple Choice

Which opioid is primarily metabolized by plasma esterases?

Explanation:
Remifentanil is primarily metabolized by plasma esterases, which are enzymes found in the blood that break down the drug quickly. This property gives remifentanil a very short half-life, making it particularly useful in situations where rapid onset and offset of analgesia are desired, such as in surgical procedures or during sedation. Unlike remifentanil, fentanyl, morphine, and oxycodone undergo a different metabolic process, primarily involving liver metabolism through cytochrome P450 enzymes. This difference in metabolism is significant in clinical practice, as the rapid breakdown of remifentanil allows for precise control of analgesia and quicker recovery times for patients post-surgery.

Remifentanil is primarily metabolized by plasma esterases, which are enzymes found in the blood that break down the drug quickly. This property gives remifentanil a very short half-life, making it particularly useful in situations where rapid onset and offset of analgesia are desired, such as in surgical procedures or during sedation.

Unlike remifentanil, fentanyl, morphine, and oxycodone undergo a different metabolic process, primarily involving liver metabolism through cytochrome P450 enzymes. This difference in metabolism is significant in clinical practice, as the rapid breakdown of remifentanil allows for precise control of analgesia and quicker recovery times for patients post-surgery.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy